node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ettA | infB | CN09_04910 | CN09_34190 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | 0.852 |
ettA | rlmE | CN09_04910 | CN09_15985 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit | 0.848 |
ettA | rplA | CN09_04910 | CN09_08950 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release | 0.935 |
ettA | rplB | CN09_04910 | CN09_08880 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome | 0.923 |
ettA | rplC | CN09_04910 | CN09_08895 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit | 0.857 |
ettA | rplE | CN09_04910 | CN09_08835 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs | 0.907 |
ettA | rplO | CN09_04910 | CN09_08800 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 50S ribosomal protein L15; Binds to the 23S rRNA | 0.854 |
ettA | rplW | CN09_04910 | CN09_08885 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome | 0.866 |
ettA | rpsL | CN09_04910 | CN09_08920 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | Small subunit ribosomal protein s12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit | 0.909 |
ettA | rpsN | CN09_04910 | CN09_08830 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site | 0.894 |
infB | ettA | CN09_34190 | CN09_04910 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.852 |
infB | rlmE | CN09_34190 | CN09_15985 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit | 0.970 |
infB | rplA | CN09_34190 | CN09_08950 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release | 0.995 |
infB | rplB | CN09_34190 | CN09_08880 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome | 0.999 |
infB | rplC | CN09_34190 | CN09_08895 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit | 0.999 |
infB | rplE | CN09_34190 | CN09_08835 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs | 0.992 |
infB | rplO | CN09_34190 | CN09_08800 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | 50S ribosomal protein L15; Binds to the 23S rRNA | 0.999 |
infB | rplW | CN09_34190 | CN09_08885 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome | 0.996 |
infB | rpsL | CN09_34190 | CN09_08920 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | Small subunit ribosomal protein s12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit | 0.999 |
infB | rpsN | CN09_34190 | CN09_08830 | Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site | 0.998 |