STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvNAcetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology (190 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology
  
  
 0.999
CN09_05420
Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology
 0.999
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
 
 0.999
CN09_12740
Acetolactate synthase catalytic subunit; Catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; catalytic; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family
 0.991
CN09_04885
Thiamine pyrophosphate-binding protein; Belongs to the TPP enzyme family
 
 0.990
CN09_21830
Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology
  
 0.986
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family
 
 
 0.931
polA
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
       0.914
CN09_16980
Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology
 
  
 0.908
CN09_34110
Prephenate dehydratase; Catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology
 
  
 0.901
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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