node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_05700 | CN09_05710 | CN09_05700 | CN09_05710 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology | Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_05700 | CN09_05715 | CN09_05700 | CN09_05715 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology | Belongs to the methylenetetrahydrofolate reductase family | 0.971 |
CN09_05700 | CN09_05720 | CN09_05700 | CN09_05720 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology | Methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.972 |
CN09_05700 | CN09_05725 | CN09_05700 | CN09_05725 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_05700 | metH | CN09_05700 | CN09_04750 | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate | 0.999 |
CN09_05710 | CN09_05700 | CN09_05710 | CN09_05700 | Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_05710 | CN09_05715 | CN09_05710 | CN09_05715 | Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | Belongs to the methylenetetrahydrofolate reductase family | 0.951 |
CN09_05710 | CN09_05720 | CN09_05710 | CN09_05720 | Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | Methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.837 |
CN09_05710 | CN09_05725 | CN09_05710 | CN09_05725 | Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.972 |
CN09_05710 | CN09_07710 | CN09_05710 | CN09_07710 | Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | 0.436 |
CN09_05710 | CN09_17085 | CN09_05710 | CN09_17085 | Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | 0.798 |
CN09_05710 | gcvP | CN09_05710 | CN09_06885 | Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein | 0.627 |
CN09_05710 | nnrD | CN09_05710 | CN09_07485 | Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.461 |
CN09_05715 | CN09_05700 | CN09_05715 | CN09_05700 | Belongs to the methylenetetrahydrofolate reductase family | Drug:proton antiporter; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.971 |
CN09_05715 | CN09_05710 | CN09_05715 | CN09_05710 | Belongs to the methylenetetrahydrofolate reductase family | Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.951 |
CN09_05715 | CN09_05720 | CN09_05715 | CN09_05720 | Belongs to the methylenetetrahydrofolate reductase family | Methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.998 |
CN09_05715 | CN09_05725 | CN09_05715 | CN09_05725 | Belongs to the methylenetetrahydrofolate reductase family | Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.977 |
CN09_05715 | CN09_07710 | CN09_05715 | CN09_07710 | Belongs to the methylenetetrahydrofolate reductase family | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | 0.796 |
CN09_05715 | CN09_17085 | CN09_05715 | CN09_17085 | Belongs to the methylenetetrahydrofolate reductase family | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | 0.999 |
CN09_05715 | gcvP | CN09_05715 | CN09_06885 | Belongs to the methylenetetrahydrofolate reductase family | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein | 0.967 |