node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_03380 | CN09_05870 | CN09_03380 | CN09_05870 | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.932 |
CN09_05870 | CN09_03380 | CN09_05870 | CN09_03380 | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | 2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.932 |
CN09_05870 | cobA | CN09_05870 | CN09_05860 | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | Uroporphyrin-iii methyltransferase; Belongs to the precorrin methyltransferase family | 0.930 |
CN09_05870 | cobB | CN09_05870 | CN09_05865 | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source | 0.992 |
CN09_05870 | cobD | CN09_05870 | CN09_05875 | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | Cobalamin biosynthesis protein cobd; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group | 0.996 |
CN09_05870 | cobO | CN09_05870 | CN09_05830 | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | Cobinamide adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | 0.930 |
CN09_05870 | cobQ | CN09_05870 | CN09_05795 | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | Cobalamin biosynthesis protein cobq; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation | 0.957 |
CN09_05870 | cobS | CN09_05870 | CN09_06075 | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate | 0.924 |
CN09_05870 | cobT | CN09_05870 | CN09_06080 | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB) | 0.933 |
CN09_05870 | cobU | CN09_05870 | CN09_05810 | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | Cobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate | 0.927 |
CN09_05870 | hisD | CN09_05870 | CN09_20020 | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine | 0.930 |
cobA | CN09_05870 | CN09_05860 | CN09_05870 | Uroporphyrin-iii methyltransferase; Belongs to the precorrin methyltransferase family | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.930 |
cobA | cobB | CN09_05860 | CN09_05865 | Uroporphyrin-iii methyltransferase; Belongs to the precorrin methyltransferase family | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source | 0.964 |
cobA | cobD | CN09_05860 | CN09_05875 | Uroporphyrin-iii methyltransferase; Belongs to the precorrin methyltransferase family | Cobalamin biosynthesis protein cobd; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group | 0.951 |
cobA | cobO | CN09_05860 | CN09_05830 | Uroporphyrin-iii methyltransferase; Belongs to the precorrin methyltransferase family | Cobinamide adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids | 0.588 |
cobA | cobQ | CN09_05860 | CN09_05795 | Uroporphyrin-iii methyltransferase; Belongs to the precorrin methyltransferase family | Cobalamin biosynthesis protein cobq; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation | 0.686 |
cobA | cobS | CN09_05860 | CN09_06075 | Uroporphyrin-iii methyltransferase; Belongs to the precorrin methyltransferase family | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate | 0.710 |
cobA | cobT | CN09_05860 | CN09_06080 | Uroporphyrin-iii methyltransferase; Belongs to the precorrin methyltransferase family | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB) | 0.646 |
cobA | cobU | CN09_05860 | CN09_05810 | Uroporphyrin-iii methyltransferase; Belongs to the precorrin methyltransferase family | Cobalamin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate | 0.734 |
cobB | CN09_05870 | CN09_05865 | CN09_05870 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source | Alpha-ribazole phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.992 |