STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CN09_05915Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology (244 aa)    
Predicted Functional Partners:
CN09_15420
Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology
     
 0.999
CN09_12395
Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology
 
  
 0.978
CN09_19725
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology
  
  
 0.955
CN09_11810
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology
     
 0.937
CN09_00240
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology
     
 0.934
CN09_03650
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology
   
 
 0.934
CN09_03380
2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology
 
   
 0.913
pleD
Response regulator PleD; Involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; Derived by automated computational analysis using gene prediction method: Protein Homology
  
  
 0.910
CN09_03065
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology
   
 
 0.893
putA
Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family
     
 0.884
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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