| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CN09_01820 | CN09_07015 | CN09_01820 | CN09_07015 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde | Serine dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.765 |
| CN09_01820 | gcvP | CN09_01820 | CN09_06885 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.999 |
| CN09_01820 | glyA | CN09_01820 | CN09_10385 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.847 |
| CN09_01820 | lipA | CN09_01820 | CN09_07790 | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | 0.446 |
| CN09_07015 | CN09_01820 | CN09_07015 | CN09_01820 | Serine dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde | 0.765 |
| CN09_07015 | gcvH | CN09_07015 | CN09_06890 | Serine dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | 0.731 |
| CN09_07015 | gcvP | CN09_07015 | CN09_06885 | Serine dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.999 |
| CN09_07015 | gcvT | CN09_07015 | CN09_06895 | Serine dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology | Glycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.622 |
| CN09_07015 | glyA | CN09_07015 | CN09_10385 | Serine dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.935 |
| CN09_07015 | lipA | CN09_07015 | CN09_07790 | Serine dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | 0.524 |
| CN09_10370 | aroK | CN09_10370 | CN09_27630 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method- Protein Homology | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family | 0.674 |
| CN09_10370 | gcvH | CN09_10370 | CN09_06890 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method- Protein Homology | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | 0.528 |
| CN09_10370 | gcvP | CN09_10370 | CN09_06885 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method- Protein Homology | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.999 |
| CN09_10370 | glyA | CN09_10370 | CN09_10385 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method- Protein Homology | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.977 |
| CN09_10370 | lipA | CN09_10370 | CN09_07790 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method- Protein Homology | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | 0.417 |
| CN09_10370 | pdxJ | CN09_10370 | CN09_05475 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method- Protein Homology | Pyridoxine 5’-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5’-phosphate (PNP) and inorganic phosphate | 0.562 |
| aroK | CN09_10370 | CN09_27630 | CN09_10370 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.674 |
| aroK | gcvP | CN09_27630 | CN09_06885 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family | 0.999 |
| aroK | glyA | CN09_27630 | CN09_10385 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.488 |
| gcvH | CN09_07015 | CN09_06890 | CN09_07015 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein | Serine dehydratase; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.731 |
