hisI protein (Agrobacterium rhizogenes) - STRING interaction network

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hisI

Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (149 aa)

Predicted Functional Partners:

CN09_01825

0.999

CN09_03985

0.999

nnrD

0.999

CN09_10375

0.999

hisB

0.999

hisF

0.999

hisD

0.999

hisA

0.998

hisE

0.997

hisG

0.996

Your Current Organism:

Agrobacterium rhizogenes

NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CN09_01825	CN09_03985	CN09_01825	CN09_03985	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology	0.999
CN09_01825	CN09_10375	CN09_01825	CN09_10375	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.999
CN09_01825	hisA	CN09_01825	CN09_17485	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Derived by automated computational analysis using gene prediction method: Protein Homology	0.922
CN09_01825	hisB	CN09_01825	CN09_17470	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology	0.997
CN09_01825	hisD	CN09_01825	CN09_20020	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	0.999
CN09_01825	hisE	CN09_01825	CN09_17495	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	Phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology	0.999
CN09_01825	hisF	CN09_01825	CN09_17490	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	0.999
CN09_01825	hisG	CN09_01825	CN09_16190	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity; Belongs to the ATP phosphoribosyltransferase family. Short subfamily	0.999
CN09_01825	hisI	CN09_01825	CN09_07080	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	0.999
CN09_01825	nnrD	CN09_01825	CN09_07485	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.912
CN09_03985	CN09_01825	CN09_03985	CN09_01825	Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	0.999
CN09_03985	CN09_10375	CN09_03985	CN09_10375	Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.999
CN09_03985	hisA	CN09_03985	CN09_17485	Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Derived by automated computational analysis using gene prediction method: Protein Homology	0.999
CN09_03985	hisB	CN09_03985	CN09_17470	Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology	Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology	0.990
CN09_03985	hisD	CN09_03985	CN09_20020	Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	0.953
CN09_03985	hisE	CN09_03985	CN09_17495	Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology	Phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology	0.999
CN09_03985	hisF	CN09_03985	CN09_17490	Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology	Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	0.998
CN09_03985	hisG	CN09_03985	CN09_16190	Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity; Belongs to the ATP phosphoribosyltransferase family. Short subfamily	0.986
CN09_03985	hisI	CN09_03985	CN09_07080	Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology	Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	0.999
CN09_10375	CN09_01825	CN09_10375	CN09_01825	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate; In the C-terminal section; belongs to the HTP reductase family	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology	0.999

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