node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_03985 | gltB | CN09_03985 | CN09_01825 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_03985 | guaA | CN09_03985 | CN09_14055 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 0.612 |
CN09_03985 | hisA | CN09_03985 | CN09_17485 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_03985 | hisB | CN09_03985 | CN09_17470 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_03985 | hisD | CN09_03985 | CN09_20020 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine | 0.983 |
CN09_03985 | hisF | CN09_03985 | CN09_17490 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit | 0.999 |
CN09_03985 | hisG | CN09_03985 | CN09_16190 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Atp phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity | 0.999 |
CN09_03985 | hisI | CN09_03985 | CN09_07080 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | Phosphoribosyl-amp cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP | 0.999 |
CN09_03985 | ribD | CN09_03985 | CN09_10375 | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate | 0.999 |
gltB | CN09_03985 | CN09_01825 | CN09_03985 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
gltB | guaA | CN09_01825 | CN09_14055 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Gmp synthase; Catalyzes the synthesis of GMP from XMP | 0.999 |
gltB | hisA | CN09_01825 | CN09_17485 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
gltB | hisB | CN09_01825 | CN09_17470 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Imidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
gltB | hisD | CN09_01825 | CN09_20020 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine | 0.999 |
gltB | hisF | CN09_01825 | CN09_17490 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit | 0.999 |
gltB | hisG | CN09_01825 | CN09_16190 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Atp phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity | 0.999 |
gltB | hisI | CN09_01825 | CN09_07080 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Phosphoribosyl-amp cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP | 0.999 |
gltB | nnrD | CN09_01825 | CN09_07485 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.901 |
gltB | ribD | CN09_01825 | CN09_10375 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate | 0.999 |
guaA | CN09_03985 | CN09_14055 | CN09_03985 | Gmp synthase; Catalyzes the synthesis of GMP from XMP | Anthranilate synthase; trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.612 |