| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CN09_01860 | CN09_07310 | CN09_01860 | CN09_07310 | D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.990 |
| CN09_01860 | guaB | CN09_01860 | CN09_16005 | D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily | Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family | 0.908 |
| CN09_01860 | pheT | CN09_01860 | CN09_13825 | D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily | Phenylalanine--tRNA ligase beta subunit; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily | 0.568 |
| CN09_01860 | polA | CN09_01860 | CN09_13050 | D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity | 0.455 |
| CN09_01860 | tmk | CN09_01860 | CN09_07305 | D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis | 0.839 |
| CN09_07300 | CN09_07310 | CN09_07300 | CN09_07310 | D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the peptidase S11 family | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.983 |
| CN09_07300 | guaB | CN09_07300 | CN09_16005 | D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the peptidase S11 family | Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family | 0.602 |
| CN09_07300 | tmk | CN09_07300 | CN09_07305 | D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the peptidase S11 family | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis | 0.978 |
| CN09_07310 | CN09_01860 | CN09_07310 | CN09_01860 | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily | 0.990 |
| CN09_07310 | CN09_07300 | CN09_07310 | CN09_07300 | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the peptidase S11 family | 0.983 |
| CN09_07310 | CN09_14165 | CN09_07310 | CN09_14165 | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] | 0.941 |
| CN09_07310 | CN09_17755 | CN09_07310 | CN09_17755 | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.995 |
| CN09_07310 | dnaX | CN09_07310 | CN09_34140 | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity | 0.987 |
| CN09_07310 | guaB | CN09_07310 | CN09_16005 | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family | 0.955 |
| CN09_07310 | pheT | CN09_07310 | CN09_13825 | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | Phenylalanine--tRNA ligase beta subunit; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily | 0.930 |
| CN09_07310 | polA | CN09_07310 | CN09_13050 | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity | 0.965 |
| CN09_07310 | tmk | CN09_07310 | CN09_07305 | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis | 0.999 |
| CN09_07310 | topA | CN09_07310 | CN09_09825 | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA super [...] | 0.999 |
| CN09_14165 | CN09_07310 | CN09_14165 | CN09_07310 | Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3’-end of a DNA strand; the delta’ subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.941 |
| CN09_14165 | CN09_17755 | CN09_14165 | CN09_17755 | Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method- Protein Homology | 0.714 |
