lpxD protein (Agrobacterium rhizogenes) - STRING interaction network

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lpxD

UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily (355 aa)

Predicted Functional Partners:

lpxA

0.999

fabZ

0.999

CN09_07865

0.999

CN09_07870

0.999

CN09_17560

0.999

nnrD

0.999

polA

0.999

bamA

0.998

CN09_01860

0.989

lpxC

0.987

Your Current Organism:

Agrobacterium rhizogenes

NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CN09_01860	CN09_07865	CN09_01860	CN09_07865	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	0.999
CN09_01860	CN09_07870	CN09_01860	CN09_07870	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology	0.994
CN09_01860	CN09_17560	CN09_01860	CN09_17560	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	Chlorosome protein; Derived by automated computational analysis using gene prediction method- Protein Homology	0.999
CN09_01860	bamA	CN09_01860	CN09_07890	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	0.943
CN09_01860	fabZ	CN09_01860	CN09_07880	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	0.729
CN09_01860	lpxA	CN09_01860	CN09_07875	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	0.996
CN09_01860	lpxC	CN09_01860	CN09_05085	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family	0.983
CN09_01860	lpxD	CN09_01860	CN09_07885	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily	0.989
CN09_01860	nnrD	CN09_01860	CN09_07485	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family	0.999
CN09_01860	polA	CN09_01860	CN09_13050	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity	0.455
CN09_07865	CN09_01860	CN09_07865	CN09_01860	Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	0.999
CN09_07865	CN09_07870	CN09_07865	CN09_07870	Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology	0.999
CN09_07865	bamA	CN09_07865	CN09_07890	Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	0.976
CN09_07865	fabZ	CN09_07865	CN09_07880	Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	0.999
CN09_07865	lpxA	CN09_07865	CN09_07875	Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	0.999
CN09_07865	lpxC	CN09_07865	CN09_05085	Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family	0.987
CN09_07865	lpxD	CN09_07865	CN09_07885	Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily	0.999
CN09_07870	CN09_01860	CN09_07870	CN09_01860	Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology	D-arabinose 5-phosphate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the SIS family. GutQ/KpsF subfamily	0.994
CN09_07870	CN09_07865	CN09_07870	CN09_07865	Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	0.999
CN09_07870	bamA	CN09_07870	CN09_07890	Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology	Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	0.974

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