node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_08585 | CN09_16950 | CN09_08585 | CN09_16950 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | Hypothetical protein; Belongs to the UPF0301 (AlgH) family | 0.998 |
CN09_08585 | CN09_27465 | CN09_08585 | CN09_27465 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | Sodium:dicarboxylate symporter; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.987 |
CN09_08585 | CN09_28260 | CN09_08585 | CN09_28260 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | Thiol:disulfide interchange protein CycY; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.987 |
CN09_08585 | dut | CN09_08585 | CN09_14245 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | 0.896 |
CN09_08585 | grxC | CN09_08585 | CN09_27260 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins | 0.990 |
CN09_08585 | ndk | CN09_08585 | CN09_10590 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | Phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate | 0.935 |
CN09_08585 | nrdF | CN09_08585 | CN09_20680 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides | 0.997 |
CN09_08585 | nrdH | CN09_08585 | CN09_20665 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.993 |
CN09_08585 | pyrH | CN09_08585 | CN09_07915 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP | 0.933 |
CN09_08585 | thyA | CN09_08585 | CN09_05290 | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis | 0.894 |
CN09_16950 | CN09_08585 | CN09_16950 | CN09_08585 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | 0.998 |
CN09_16950 | CN09_27465 | CN09_16950 | CN09_27465 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family | Sodium:dicarboxylate symporter; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.993 |
CN09_16950 | CN09_28260 | CN09_16950 | CN09_28260 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family | Thiol:disulfide interchange protein CycY; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.993 |
CN09_16950 | dut | CN09_16950 | CN09_14245 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA | 0.854 |
CN09_16950 | grxC | CN09_16950 | CN09_27260 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family | Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins | 0.992 |
CN09_16950 | nrdH | CN09_16950 | CN09_20665 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family | Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.992 |
CN09_16950 | thyA | CN09_16950 | CN09_05290 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis | 0.853 |
CN09_27465 | CN09_08585 | CN09_27465 | CN09_08585 | Sodium:dicarboxylate symporter; Derived by automated computational analysis using gene prediction method: Protein Homology | Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen | 0.987 |
CN09_27465 | CN09_16950 | CN09_27465 | CN09_16950 | Sodium:dicarboxylate symporter; Derived by automated computational analysis using gene prediction method: Protein Homology | Hypothetical protein; Belongs to the UPF0301 (AlgH) family | 0.993 |
CN09_27465 | CN09_28260 | CN09_27465 | CN09_28260 | Sodium:dicarboxylate symporter; Derived by automated computational analysis using gene prediction method: Protein Homology | Thiol:disulfide interchange protein CycY; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.507 |