node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_10350 | CN09_10370 | CN09_10350 | CN09_10370 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.980 |
CN09_10350 | CN09_15290 | CN09_10350 | CN09_15290 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | Hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.582 |
CN09_10350 | CN09_16240 | CN09_10350 | CN09_16240 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | Riboflavin kinase; Belongs to the ribF family | 0.875 |
CN09_10350 | CN09_17085 | CN09_10350 | CN09_17085 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | 0.793 |
CN09_10350 | glyA | CN09_10350 | CN09_10385 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.758 |
CN09_10350 | ispDF | CN09_10350 | CN09_07765 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) | 0.860 |
CN09_10350 | nrdR | CN09_10350 | CN09_10380 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | Nrdr family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes | 0.425 |
CN09_10350 | ribB | CN09_10350 | CN09_16765 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | 0.999 |
CN09_10350 | ribD | CN09_10350 | CN09_10375 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate | 0.999 |
CN09_10370 | CN09_10350 | CN09_10370 | CN09_10350 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | 0.980 |
CN09_10370 | CN09_15290 | CN09_10370 | CN09_15290 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | Hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.945 |
CN09_10370 | CN09_16240 | CN09_10370 | CN09_16240 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | Riboflavin kinase; Belongs to the ribF family | 0.927 |
CN09_10370 | CN09_17085 | CN09_10370 | CN09_17085 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family | 0.997 |
CN09_10370 | gcvP | CN09_10370 | CN09_06885 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein | 0.999 |
CN09_10370 | glyA | CN09_10370 | CN09_10385 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism | 0.977 |
CN09_10370 | ispDF | CN09_10370 | CN09_07765 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) | 0.977 |
CN09_10370 | nrdR | CN09_10370 | CN09_10380 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | Nrdr family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes | 0.943 |
CN09_10370 | ribB | CN09_10370 | CN09_16765 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate | 0.999 |
CN09_10370 | ribD | CN09_10370 | CN09_10375 | Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate | 0.999 |
CN09_15290 | CN09_10350 | CN09_15290 | CN09_10350 | Hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin | 0.582 |