STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily (245 aa)    
Predicted Functional Partners:
cysD
Sulfate adenylyltransferase subunit 2; With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology
  
 0.999
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily
 
 
 0.999
CN09_18560
Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology
   
 
 0.999
CN09_07700
Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology
 
 0.993
CN09_07710
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme; In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family
 
  
 0.993
cysW
Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; Derived by automated computational analysis using gene prediction method: Protein Homology
 
  
 0.988
cysA
Sulfate/thiosulfate import ATP-binding protein CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family
 
  
 0.962
CN09_24120
Sulfate transporter subunit; Derived by automated computational analysis using gene prediction method: Protein Homology
 
  
 0.955
CN09_07695
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology
     0.902
CN09_24115
Sulfate/thiosulfate transporter subunit; Derived by automated computational analysis using gene prediction method: Protein Homology
 
  
 0.874
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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