STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polAIn addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity (1000 aa)    
Predicted Functional Partners:
CN09_00240
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology
     
 0.999
CN09_00705
Hypothetical protein; Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology
  
 0.999
nth
Endonuclease iii; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate
 
 
 0.999
CN09_01195
6-O-methylguanine DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology
   
 
 0.999
gltX
Glutamyl-trna synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
     
 0.999
cpsB
mannose-1-phosphate guanyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family
     
 0.999
gltB
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology
  
  
 0.999
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX
  
    0.999
pyk
Belongs to the pyruvate kinase family
  
    0.999
rpmE
50S ribosomal protein L31; Binds the 23S rRNA
 
   
 0.999
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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