proA protein (Agrobacterium rhizogenes) - STRING interaction network

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proA

Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate; Belongs to the gamma-glutamyl phosphate reductase family (427 aa)

Predicted Functional Partners:

CN09_10375

0.999

proB

0.999

rsfS

0.999

polA

0.997

nadD

0.985

obgE

0.968

argC

0.929

ribB

0.912

argH

0.896

guaA

0.882

Your Current Organism:

Agrobacterium rhizogenes

NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CN09_10375	argC	CN09_10375	CN09_10190	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde; Belongs to the NAGSA dehydrogenase family. Type 2 subfamily	0.817
CN09_10375	argH	CN09_10375	CN09_27470	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	Argininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method- Protein Homology	0.871
CN09_10375	guaA	CN09_10375	CN09_14055	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.965
CN09_10375	nadD	CN09_10375	CN09_17985	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	0.883
CN09_10375	polA	CN09_10375	CN09_13050	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity	0.975
CN09_10375	proA	CN09_10375	CN09_17990	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate; Belongs to the gamma-glutamyl phosphate reductase family	0.999
CN09_10375	ribB	CN09_10375	CN09_16765	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family	0.999
argC	CN09_10375	CN09_10190	CN09_10375	N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde; Belongs to the NAGSA dehydrogenase family. Type 2 subfamily	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.817
argC	argH	CN09_10190	CN09_27470	N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde; Belongs to the NAGSA dehydrogenase family. Type 2 subfamily	Argininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method- Protein Homology	0.992
argC	guaA	CN09_10190	CN09_14055	N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde; Belongs to the NAGSA dehydrogenase family. Type 2 subfamily	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	0.874
argC	polA	CN09_10190	CN09_13050	N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde; Belongs to the NAGSA dehydrogenase family. Type 2 subfamily	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity	0.999
argC	proA	CN09_10190	CN09_17990	N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde; Belongs to the NAGSA dehydrogenase family. Type 2 subfamily	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate; Belongs to the gamma-glutamyl phosphate reductase family	0.929
argC	proB	CN09_10190	CN09_17995	N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde; Belongs to the NAGSA dehydrogenase family. Type 2 subfamily	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	0.931
argC	ribB	CN09_10190	CN09_16765	N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde; Belongs to the NAGSA dehydrogenase family. Type 2 subfamily	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family	0.999
argH	CN09_10375	CN09_27470	CN09_10375	Argininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method- Protein Homology	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.871
argH	argC	CN09_27470	CN09_10190	Argininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method- Protein Homology	N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde; Belongs to the NAGSA dehydrogenase family. Type 2 subfamily	0.992
argH	nadD	CN09_27470	CN09_17985	Argininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method- Protein Homology	Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	0.607
argH	proA	CN09_27470	CN09_17990	Argininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method- Protein Homology	Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate; Belongs to the gamma-glutamyl phosphate reductase family	0.896
argH	proB	CN09_27470	CN09_17995	Argininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method- Protein Homology	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	0.934
guaA	CN09_10375	CN09_14055	CN09_10375	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP	Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5’-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5’-phosphate; In the C-terminal section; belongs to the HTP reductase family	0.965

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