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yacG protein (Agrobacterium rhizogenes) - STRING interaction network
"yacG" - DNA gyrase inhibitor YacG in Agrobacterium rhizogenes
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second shell of interactors
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proteins of unknown 3D structure
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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yacGDNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (71 aa)    
Predicted Functional Partners:
CN09_20040
Maf-like protein CN09_20040; Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Derived by automated computational analysis using gene prediction method- Protein Homology (206 aa)
              0.976
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex (72 aa)
              0.904
CN09_20030
Arsenate reductase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family (155 aa)
              0.838
CN09_20025
UPF0262 protein CN09_20025; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the UPF0262 family (157 aa)
              0.838
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (432 aa)
              0.838
CN09_20015
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (147 aa)
              0.818
pgi
Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the GPI family (541 aa)
              0.744
CN09_02215
Uncharacterized protein; Derived by automated computational analysis using gene prediction method- Protein Homology (91 aa)
   
          0.731
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner (934 aa)
     
 
  0.709
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity; Belongs to the ATP phosphoribosyltransferase family. Short subfamily (237 aa)
              0.707
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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