node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CN09_07710 | CN09_23610 | CN09_07710 | CN09_23610 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | 0.975 |
CN09_07710 | CN09_23615 | CN09_07710 | CN09_23615 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | precorrin-3B C17-methyltransferase; Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_07710 | cbiE | CN09_07710 | CN09_23625 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Precorrin-6Y methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_07710 | cobB | CN09_07710 | CN09_05865 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source | 0.999 |
CN09_07710 | cobD | CN09_07710 | CN09_05875 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Cobalamin biosynthesis protein cobd; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group | 0.999 |
CN09_07710 | cobG | CN09_07710 | CN09_23600 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Precorrin-3B synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_07710 | cobH | CN09_07710 | CN09_23605 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | precorrin-8X methylmutase; Catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_07710 | cobM | CN09_07710 | CN09_23630 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family | 0.999 |
CN09_07710 | cobQ | CN09_07710 | CN09_05795 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | Cobalamin biosynthesis protein cobq; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation | 0.999 |
CN09_23610 | CN09_07710 | CN09_23610 | CN09_07710 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | 0.975 |
CN09_23610 | CN09_23615 | CN09_23610 | CN09_23615 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | precorrin-3B C17-methyltransferase; Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_23610 | cbiE | CN09_23610 | CN09_23625 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | Precorrin-6Y methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_23610 | cobB | CN09_23610 | CN09_05865 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source | 0.949 |
CN09_23610 | cobD | CN09_23610 | CN09_05875 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | Cobalamin biosynthesis protein cobd; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group | 0.936 |
CN09_23610 | cobG | CN09_23610 | CN09_23600 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | Precorrin-3B synthase; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.989 |
CN09_23610 | cobH | CN09_23610 | CN09_23605 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | precorrin-8X methylmutase; Catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.993 |
CN09_23610 | cobM | CN09_23610 | CN09_23630 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family | 0.991 |
CN09_23610 | cobQ | CN09_23610 | CN09_05795 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | Cobalamin biosynthesis protein cobq; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation | 0.932 |
CN09_23610 | cobW | CN09_23610 | CN09_05815 | precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family | Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology | 0.999 |
CN09_23615 | CN09_07710 | CN09_23615 | CN09_07710 | precorrin-3B C17-methyltransferase; Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme | 0.999 |