STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CN09_23615precorrin-3B C17-methyltransferase; Catalyzes the formation of precorrin-4 from precorrin-3B and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology (254 aa)    
Predicted Functional Partners:
cobW
Cobalamin biosynthesis protein CobW; Derived by automated computational analysis using gene prediction method: Protein Homology
 
   
 0.999
CN09_07710
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
   
 0.999
cobH
precorrin-8X methylmutase; Catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology
  
 0.999
CN09_23610
precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family
  
 0.999
cbiE
Precorrin-6Y methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology
 
  
 0.999
cobM
precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family
  
 0.999
cobQ
Cobalamin biosynthesis protein cobq; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
  
 0.993
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source
  
 0.991
cobD
Cobalamin biosynthesis protein cobd; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
  
 0.991
cobG
Precorrin-3B synthase; Derived by automated computational analysis using gene prediction method: Protein Homology
 
  
 0.989
Your Current Organism:
Agrobacterium rhizogenes
NCBI taxonomy Id: 359
Other names: A. rhizogenes, ATCC 11325, Agrobacterium biovar 2, Agrobacterium genomic group 10, Agrobacterium genomic species 10, Agrobacterium genomosp. 10, Agrobacterium rhizogenes (RI plasmid PRI1724), Agrobacterium rhizogenes (RI plasmid PRI8196), Agrobacterium rhizogenes (RI plasmid PRIA4B), CFBP 5520, CIP 104328, DSM 30148, ICMP 5794, IFO 13257, JCM 20919, LMG 150, NBRC 13257, NCPPB 2991, Rhizobium rhizogenes, Rhizobium sp. LMG 9509
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