STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAB1_0510Serine/threonine dehydratase, pyridoxal-phosphate attachment site:Pyridoxal-5'-phosphate-dependent enzyme, beta family:Threon. (463 aa)    
Predicted Functional Partners:
BAB1_1293
Homoserine dehydrogenase:Amino acid-binding ACT:Homoserine dehydrogenase, NAD binding domain.
 
 0.988
BAB1_1874
Aspartokinase; Aspartate/glutamate/uridylate kinase:Glutamate 5-kinase:Aspartate kinase:Amino acid-binding ACT:Aspartate kinase, monofunctio..; Belongs to the aspartokinase family.
  
 
 0.909
leuD
Aconitate hydratase, C-terminal:3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
  
 0.891
thrB
Aminoglycoside phosphotransferase:Homoserine kinase ThrB; Belongs to the pseudomonas-type ThrB family.
    
 0.816
serC
Sugar transporter superfamily:Phosphoserine aminotransferase, Methanosarcina type; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 0.790
ilvC
Acetohydroxy acid isomeroreductase:Aromatic-ring hydroxylase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.774
BAB1_1410
Phosphoserine phosphatase SerB:Haloacid dehalogenase-like hydrolase:HAD-superfamily hydrolase, subfamily IB (PSPase-like).
   
 0.753
BAB2_0051
Low-specificity threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
   
 0.707
gltB
Glutamate synthase amidotransferase domain:Glutamate synthase central domain.
  
  
 0.697
ilvN
Amino acid-binding ACT:Acetolactate synthase, small subunit.
  
  
 0.690
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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