STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAB2_1164ParB-like nuclease:ParB-like partition protein; Belongs to the ParB family. (328 aa)    
Predicted Functional Partners:
BAB2_1163
NifH/frxC family:ATPase, ParA type.
 
 
 0.979
repC
Replication protein C.
 
   
 0.827
BAB1_0964
Conserved hypothetical protein.
    
 
 0.819
BAB1_2060
NifH/frxC family:ATPase, ParA type.
  
 
 0.783
rsmG
Glucose inhibited division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
  
  
 0.690
BAB2_0413
Putative peptidoglycan binding domain 1:Sel1-like repeat.
  
 
 0.451
BAB1_1293
Homoserine dehydrogenase:Amino acid-binding ACT:Homoserine dehydrogenase, NAD binding domain.
     
 0.429
ftsZ
Cell division protein FtsZ:Tubulin family:Proline-rich region:Tubulin/FtsZ protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.421
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
     
 0.415
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.413
Your Current Organism:
Brucella abortus
NCBI taxonomy Id: 359391
Other names: B. abortus 2308, Brucella abortus 2308, Brucella melitensis biovar Abortus 2308
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