node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABM45425.1 | guaA | BARBAKC583_0289 | BARBAKC583_0344 | Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.493 |
ABM45425.1 | panC | BARBAKC583_0289 | BARBAKC583_0476 | Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.900 |
cmk | guaA | BARBAKC583_1304 | BARBAKC583_0344 | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.549 |
cmk | panC | BARBAKC583_1304 | BARBAKC583_0476 | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.904 |
coaA | coaBC | BARBAKC583_1263 | BARBAKC583_1349 | Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.919 |
coaA | panC | BARBAKC583_1263 | BARBAKC583_0476 | Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.909 |
coaBC | coaA | BARBAKC583_1349 | BARBAKC583_1263 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Identified by match to protein family HMM PF00485; match to protein family HMM TIGR00554. | 0.919 |
coaBC | panB | BARBAKC583_1349 | BARBAKC583_0477 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.501 |
coaBC | panC | BARBAKC583_1349 | BARBAKC583_0476 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.895 |
era | lepB | BARBAKC583_0474 | BARBAKC583_0472 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | 0.824 |
era | panB | BARBAKC583_0474 | BARBAKC583_0477 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.634 |
era | panC | BARBAKC583_0474 | BARBAKC583_0476 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.651 |
era | recO | BARBAKC583_0474 | BARBAKC583_0475 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.910 |
era | rnc | BARBAKC583_0474 | BARBAKC583_0473 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.917 |
guaA | ABM45425.1 | BARBAKC583_0344 | BARBAKC583_0289 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171. | 0.493 |
guaA | cmk | BARBAKC583_0344 | BARBAKC583_1304 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.549 |
guaA | panB | BARBAKC583_0344 | BARBAKC583_0477 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.591 |
guaA | panC | BARBAKC583_0344 | BARBAKC583_0476 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.599 |
guaA | rnc | BARBAKC583_0344 | BARBAKC583_0473 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.421 |
lepB | era | BARBAKC583_0472 | BARBAKC583_0474 | Signal peptidase I; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.824 |