node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABM44765.1 | ABM44941.1 | BARBAKC583_0816 | BARBAKC583_0092 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 0.924 |
ABM44765.1 | ribD | BARBAKC583_0816 | BARBAKC583_0631 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.539 |
ABM44765.1 | ubiA | BARBAKC583_0816 | BARBAKC583_0393 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.661 |
ABM44765.1 | ubiB | BARBAKC583_0816 | BARBAKC583_1348 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.463 |
ABM44765.1 | ubiE | BARBAKC583_0816 | BARBAKC583_1347 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.956 |
ABM44765.1 | ubiG | BARBAKC583_0816 | BARBAKC583_0369 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.970 |
ABM44941.1 | ABM44765.1 | BARBAKC583_0092 | BARBAKC583_0816 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 0.924 |
ABM44941.1 | ribD | BARBAKC583_0092 | BARBAKC583_0631 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.539 |
ABM44941.1 | ubiA | BARBAKC583_0092 | BARBAKC583_0393 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.494 |
ABM44941.1 | ubiB | BARBAKC583_0092 | BARBAKC583_1348 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.445 |
ABM44941.1 | ubiE | BARBAKC583_0092 | BARBAKC583_1347 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.930 |
ABM44941.1 | ubiG | BARBAKC583_0092 | BARBAKC583_0369 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Identified by match to protein family HMM PF01494; match to protein family HMM TIGR01984; match to protein family HMM TIGR01988. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.957 |
ABM45444.1 | coaBC | BARBAKC583_0383 | BARBAKC583_1349 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.419 |
ABM45444.1 | ubiA | BARBAKC583_0383 | BARBAKC583_0393 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.915 |
ABM45444.1 | ubiE | BARBAKC583_0383 | BARBAKC583_1347 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.440 |
coaBC | ABM45444.1 | BARBAKC583_1349 | BARBAKC583_0383 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.419 |
coaBC | ribD | BARBAKC583_1349 | BARBAKC583_0631 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.591 |
coaBC | ubiB | BARBAKC583_1349 | BARBAKC583_1348 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.580 |
coaBC | ubiE | BARBAKC583_1349 | BARBAKC583_1347 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.471 |
gyrB | ribD | BARBAKC583_1346 | BARBAKC583_0631 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.456 |