STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkPhosphoglycerate kinase; Pfam match to PF00162.14 PGK; Belongs to the phosphoglycerate kinase family. (399 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
gapA
Glyceraldehyde 3-phosphate dehydrogenase A; Pfam matches to PF02800.15 Gp_dh_C, and to PF00044.19 Gp_dh_N, and to PF01113.15 DapB_N; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.999
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.989
pgm
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.987
pgi
Phosphoglucose isomerase; Pfam match to PF00342.14 PGI; Belongs to the GPI family.
 
 
 0.939
pykF
Pyruvate kinase I; Pfam matches to PF00224.16 PK, and to PF02887.11 PK_C; Belongs to the pyruvate kinase family.
 
 
 0.935
fbaA
Fructose-bisphosphate aldolase, class IIA; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.921
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
 
 
 0.795
nadD/rsfS
Fused nicotinate-mononucleotide adenylyltransferase / ribosomal silencing factor; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). Belongs to the Iojap/RsfS family.
 
   
 0.727
metK
Methionine adenosyltransferase; Pfam matches to PF02773.11 S-AdoMet_synt_C, and to PF02772.11 S-AdoMet_synt_M, and to PF00438.15 S-AdoMet_synt_N; Belongs to the AdoMet synthase family.
 
 
 0.689
Your Current Organism:
Campylobacter concisus
NCBI taxonomy Id: 360104
Other names: C. concisus 13826, Campylobacter concisus 13826, Campylobacter concisus str. 13826, Campylobacter concisus strain 13826
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