STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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[Homology]
Score
luxSS-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (171 aa)    
Predicted Functional Partners:
pfs
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
 
 
 0.981
metE
Cobalamin-independent homocysteine transmethylase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
    
 0.939
EAU00913.1
Cystathionine-beta-lyase; Pfam matches to PF01053.15 Cys_Met_Meta_PP, and to PF00266.14 Aminotran_5, and to PF00155.16 Aminotran_1_2.
  
 
 0.923
metC
Cystathionine-beta-lyase; Pfam matches to PF01053.15 Cys_Met_Meta_PP, and to PF00266.14 Aminotran_5, and to PF00155.16 Aminotran_1_2.
  
 
 0.923
metY
O-acetylhomoserine sulfhydrylase; Pfam matches to PF01053.15 Cys_Met_Meta_PP, and to PF00155.16 Aminotran_1_2, and to PF01041.12 DegT_DnrJ_EryC1, and to PF00266.14 Aminotran_5.
     
 0.903
EAT99409.1
Putative PLP-dependent C-S lyase; Pfam matches to PF00155.16 Aminotran_1_2, and to PF01053.15 Cys_Met_Meta_PP.
     
  0.900
cysK
Cysteine synthase; Pfam match to PF00291.20 PALP; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.894
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
  
  0.823
hom
Pfam matches to PF00742.14 Homoserine_dh, and to PF03447.11 NAD_binding_3, and to PF01842.20 ACT.
     
 0.813
ilvA
Threonine deaminase; Pfam matches to PF00291.20 PALP, and to PF13291.1 ACT_4, and to PF01842.20 ACT.
     
 0.805
Your Current Organism:
Campylobacter curvus
NCBI taxonomy Id: 360105
Other names: C. curvus 525.92, Campylobacter curvus 525.92, Campylobacter curvus str. 525.92, Campylobacter curvus strain 525.92
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.