STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFOrotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (226 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.991
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.942
pyrB
Aspartate carbamoyltransferase, catalytic subunit; Pfam matches to PF02729.16 OTCace_N, and to PF00185.19 OTCace; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.937
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.933
pyrD
Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
  
 0.930
carB
Carbamoylphosphate synthase, large subunit; Pfam matches to PF02786.12 CPSase_L_D2, and to PF02787.14 CPSase_L_D3, and to PF02786.12 CPSase_L_D2, and to PF00289.17 CPSase_L_chain, and to PF02142.17 MGS, and to PF00289.17 CPSase_L_chain, and to PF13535.1 ATP-grasp_4, and to PF13535.1 ATP-grasp_4, and to PF02655.9 ATP-grasp_3, and to PF02222.17 ATP-grasp, and to PF07478.8 Dala_Dala_lig_C; Belongs to the CarB family.
  
  
 0.920
surE
Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.914
carA
Carbamoylphosphate synthase, small subunit; Pfam matches to PF00988.17 CPSase_sm_chain, and to PF00117.23 GATase, and to PF07722.8 Peptidase_C26; Belongs to the CarA family.
  
  
 0.898
EAU01452.1
Pfam match to PF00860.15 Xan_ur_permease.
  
  
 0.882
pyrC2
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
  
 0.840
Your Current Organism:
Campylobacter curvus
NCBI taxonomy Id: 360105
Other names: C. curvus 525.92, Campylobacter curvus 525.92, Campylobacter curvus str. 525.92, Campylobacter curvus strain 525.92
Server load: medium (78%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.