STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argSarginyl-tRNA synthetase; Pfam matches to PF00750.14 tRNA-synt_1d, and to PF05746.10 DALR_1, and to PF03485.11 Arg_tRNA_synt_N, and to PF00133.17 tRNA-synt_1. (529 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.970
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
 
 0.970
metS
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 0.959
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
  
 0.944
gmk
Deoxyguanylate kinase / guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.917
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.891
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.891
lysS
lysyl-tRNA synthetase; Pfam matches to PF00152.15 tRNA-synt_2, and to PF01336.20 tRNA_anti-codon; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 0.887
pheT
phenylalanyl-tRNA synthetase, beta subunit; Pfam matches to PF01588.15 tRNA_bind, and to PF03147.9 FDX-ACB, and to PF03484.10 B5, and to PF03483.12 B3_4; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.866
leuS
leucyl-tRNA synthetase; Pfam matches to PF13603.1 tRNA-synt_1_2, and to PF00133.17 tRNA-synt_1, and to PF00133.17 tRNA-synt_1, and to PF09334.6 tRNA-synt_1g, and to PF09334.6 tRNA-synt_1g, and to PF08264.8 Anticodon_1; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.861
Your Current Organism:
Campylobacter curvus
NCBI taxonomy Id: 360105
Other names: C. curvus 525.92, Campylobacter curvus 525.92, Campylobacter curvus str. 525.92, Campylobacter curvus strain 525.92
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.