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MPH1 protein (Vanderwaltozyma polyspora) - STRING interaction network
"MPH1" - ATP-dependent DNA helicase MPH1 in Vanderwaltozyma polyspora
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
MPH1ATP-dependent DNA helicase MPH1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork; Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily (1012 aa)    
Predicted Functional Partners:
Kpol_340p7
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (650 aa)
     
 
  0.942
XP_001642887.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae RMI1 (YPL024W) (248 aa)
     
 
  0.931
Kpol_440p9
Uncharacterized protein; Similar to Saccharomyces cerevisiae MUS81 (YDR386W) (620 aa)
     
 
  0.927
XP_001647360.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae SGS1 (YMR190C) (1332 aa)
     
 
  0.921
XP_001645225.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae SGS1 (YMR190C) (1280 aa)
     
 
  0.921
XP_001644975.1
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism (618 aa)
     
 
  0.912
Kpol_309p8
Uncharacterized protein; Similar to Saccharomyces cerevisiae RAD10 (YML095C) (233 aa)
     
 
  0.904
XP_001642707.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae TEL2 (YGR099W) (690 aa)
       
 
  0.897
XP_001646721.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae RAD5 (YLR032W) (1178 aa)
     
 
  0.863
XP_001647137.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae YOL086W-A (103 aa)
       
 
  0.846
Your Current Organism:
Vanderwaltozyma polyspora
NCBI taxonomy Id: 36033
Other names: ATCC 22028, CBS 2163, CCRC 21397, DBVPG 6243, DSM 70294, IFO 10782, Kluyveromyces polysporus, MUCL 30238, NCYC 523, NRRL Y-8283, UCD 57-17, V. polyspora, Vanderwaltozyma polyspora, Vanderwaltozyma sp. SA20S10
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