STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MUL_2060Conserved hypothetical protein; Belongs to the UPF0102 family (122 aa)    
Predicted Functional Partners:
MUL_1240
Energy-coupling factor transport system permease protein; Membrane protein
     
 0.640
MUL_1782
annotation not available
     
 0.630
fdhD
Fdhd protein-like protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
  
    0.570
atpH
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
 
 
 0.570
MUL_2062
Conserved hypothetical membrane protein; Membrane protein
 
    0.565
nadD
Nicotinate-nucleotide adenylyltransferase nadd fused with d/s conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
 
     0.534
ruvC
Crossover junction endodeoxyribonuclease ruvc; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
 
     0.516
recX
Regulatory protein recx; Modulates RecA activity
 
  
 0.514
MUL_2029
Conserved hypothetical protein; Cytoplasmic protein
 
     0.429
MUL_0882
Conserved hypothetical protein; Membrane protein; peptidase
  
    0.412
Your Current Organism:
Mycobacterium ulcerans
NCBI taxonomy Id: 362242
Other names: M. ulcerans Agy99, Mycobacterium ulcerans Agy99, Mycobacterium ulcerans str. Agy99, Mycobacterium ulcerans strain Agy99
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