STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mshAD-inositol-3-phosphate glycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (463 aa)    
Predicted Functional Partners:
mshB
N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway
 
  
 0.891
MUL_4557
Conserved hypothetical protein; Cytoplasmic protein
  
    0.880
mshD
Mycothiol acetyltransferase, mshd; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol
 
 
 0.875
gpm1
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate
  
    0.859
mca
Mycothiol conjugate amidase mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
 
  
 0.854
MUL_4555
Transcriptional regulatory protein; Cytoplasmic protein; possibly involved in transcriptional mechanism
  
    0.804
mshC
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins
 
  
 0.743
pknG
Serine/threonine-protein kinase PknG; Detected in the secreted protein fraction by proteomics; membrane protein; involved in signal transduction (via phosphorylation) thought to regulate amino-acid uptake and stationary-phase metabolism. phosphorylates the peptide substrate myelin basic protein (MBP) at serine residues [catalytic activity: ATP + a protein = ADP + a P
 
 0.731
MUL_2200
Membrane-anchored serine/threonine-protein kinase; Membrane protein; involved in signal transduction (via phosphorylation) thought to be involved in membrane transport. phosphorylates the peptide substrate myelin basic protein (MBP) at serine and threonine residues [catalytic activity: ATP + a protein = ADP + a phosphoprotein]
  
 0.708
MUL_1252
Conserved hypothetical secreted protein; Secreted protein
  
 0.703
Your Current Organism:
Mycobacterium ulcerans
NCBI taxonomy Id: 362242
Other names: M. ulcerans Agy99, Mycobacterium ulcerans Agy99, Mycobacterium ulcerans str. Agy99, Mycobacterium ulcerans strain Agy99
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