STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
mrcA-2Multimodular transpeptidase-transglycosylase PBP 1A; COG0744 [M] Membrane carboxypeptidase (penicillin-binding protein). (772 aa)    
Predicted Functional Partners:
LSL_1088
COG0768 [M] Cell division protein FtsI/penicillin-binding protein 2.
 
 
 0.975
LSL_1053
COG0768 [M] Cell division protein FtsI/penicillin-binding protein 2.
 
 
0.969
mrcA
Multimodular transpeptidase-transglycosylase PBP 2A; COG0744 [M] Membrane carboxypeptidase (penicillin-binding protein).
  
  
 
0.925
dacC
COG1686 [M] D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.916
divIVA
Cell division initiation protein DivIVA; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
 
 0.916
dacC-2
COG1686 [M] D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.916
recU
Recombination protein; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
  
 0.898
ftsW-2
COG0772 [D] Bacterial cell division membrane protein; Belongs to the SEDS family.
 
 
 
 0.808
ftsW
Rod shape determining protein; COG0772 [D] Bacterial cell division membrane protein; Belongs to the SEDS family.
 
 
 
 0.736
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
   
 0.706
Your Current Organism:
Lactobacillus salivarius
NCBI taxonomy Id: 362948
Other names: L. salivarius UCC118, Lactobacillus salivarius UCC118, Lactobacillus salivarius str. UCC118, Lactobacillus salivarius strain UCC118, Lactobacillus salivarius subsp. salivarius UCC118
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