node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LSL_0680 | proA | LSL_0680 | LSL_1611 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.678 |
LSL_0680 | proB | LSL_0680 | LSL_1612 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.632 |
LSL_0680 | proC | LSL_0680 | LSL_1264 | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.703 |
guaA-3 | proA | LSL_1537 | LSL_1611 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.549 |
guaA-3 | proB | LSL_1537 | LSL_1612 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.493 |
guaA-3 | proC | LSL_1537 | LSL_1264 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.626 |
guaA-3 | prsA | LSL_1537 | LSL_0318 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.721 |
guaA-3 | prsA-2 | LSL_1537 | LSL_1610 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.723 |
manA | proA | LSL_1613 | LSL_1611 | COG1482 [G] Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.485 |
manA | proB | LSL_1613 | LSL_1612 | COG1482 [G] Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.491 |
manA | prsA-2 | LSL_1613 | LSL_1610 | COG1482 [G] Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.434 |
proA | LSL_0680 | LSL_1611 | LSL_0680 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | 0.678 |
proA | guaA-3 | LSL_1611 | LSL_1537 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.549 |
proA | manA | LSL_1611 | LSL_1613 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | COG1482 [G] Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.485 |
proA | proB | LSL_1611 | LSL_1612 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.999 |
proA | proC | LSL_1611 | LSL_1264 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.672 |
proA | prsA-2 | LSL_1611 | LSL_1610 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.624 |
proB | LSL_0680 | LSL_1612 | LSL_0680 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | ComE operon protein 3; COG2248 [R] Predicted hydrolase (metallo-beta-lactamase superfamily). | 0.632 |
proB | guaA-3 | LSL_1612 | LSL_1537 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.493 |
proB | manA | LSL_1612 | LSL_1613 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | COG1482 [G] Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.491 |