node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LI0494 | gmk | LI0494 | LI0310 | Hypothetical protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.934 |
LI0494 | ndk | LI0494 | LI1121 | Hypothetical protein. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.802 |
LI1171 | gmk | LI1171 | LI0310 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.900 |
LI1171 | guaA | LI1171 | LI0590 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | GMP synthase-Glutamine amidotransferase domain; Catalyzes the synthesis of GMP from XMP. | 0.937 |
LI1171 | pyrF | LI1171 | LI0311 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.900 |
LI1171 | surE | LI1171 | LI0762 | 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
gmk | LI0494 | LI0310 | LI0494 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypothetical protein. | 0.934 |
gmk | LI1171 | LI0310 | LI1171 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.900 |
gmk | guaA | LI0310 | LI0590 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase-Glutamine amidotransferase domain; Catalyzes the synthesis of GMP from XMP. | 0.961 |
gmk | ndk | LI0310 | LI1121 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.927 |
gmk | nrdA | LI0310 | LI0476 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleotide reductase large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.938 |
gmk | nrdB | LI0310 | LI0477 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Ribonucleotide reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.904 |
gmk | pykF | LI0310 | LI1095 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.928 |
gmk | pyrF | LI0310 | LI0311 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.838 |
gmk | relA | LI0310 | LI0170 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanosine polyphosphate pyrophosphohydrolases/synthetases; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.924 |
gmk | surE | LI0310 | LI0762 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
guaA | LI1171 | LI0590 | LI1171 | GMP synthase-Glutamine amidotransferase domain; Catalyzes the synthesis of GMP from XMP. | 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. | 0.937 |
guaA | gmk | LI0590 | LI0310 | GMP synthase-Glutamine amidotransferase domain; Catalyzes the synthesis of GMP from XMP. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.961 |
guaA | ndk | LI0590 | LI1121 | GMP synthase-Glutamine amidotransferase domain; Catalyzes the synthesis of GMP from XMP. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.584 |
guaA | nrdA | LI0590 | LI0476 | GMP synthase-Glutamine amidotransferase domain; Catalyzes the synthesis of GMP from XMP. | Ribonucleotide reductase large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.715 |