node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysG | cysG-2 | LI0117 | LI0320 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | 0.999 |
cysG | gltX | LI0117 | LI0462 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Glutamyl-and glutaminyl-tRNA synthetases; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.443 |
cysG | hemA | LI0117 | LI0322 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.833 |
cysG | hemB | LI0117 | LI0205 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.995 |
cysG | hemC | LI0117 | LI1011 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
cysG | hemL | LI0117 | LI0906 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Glutamate-1-semialdehyde aminotransferase. | 0.604 |
cysG | nadE | LI0117 | LI0244 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | NH(3)-dependent NAD(+) synthetase. | 0.682 |
cysG-2 | cysG | LI0320 | LI0117 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | 0.999 |
cysG-2 | ftsY | LI0320 | LI0323 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Signal renition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.498 |
cysG-2 | hemA | LI0320 | LI0322 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.835 |
cysG-2 | hemC | LI0320 | LI1011 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.816 |
cysG-2 | porA | LI0320 | LI0278 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. | 0.424 |
cysG-2 | resC | LI0320 | LI0321 | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | ABC-type transport system involved in cytochrome c biogenesis, permease component. | 0.800 |
ftsY | cysG-2 | LI0323 | LI0320 | Signal renition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | 0.498 |
ftsY | gltX | LI0323 | LI0462 | Signal renition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Glutamyl-and glutaminyl-tRNA synthetases; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.491 |
ftsY | hemA | LI0323 | LI0322 | Signal renition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.533 |
ftsY | resC | LI0323 | LI0321 | Signal renition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | ABC-type transport system involved in cytochrome c biogenesis, permease component. | 0.494 |
gltX | cysG | LI0462 | LI0117 | Glutamyl-and glutaminyl-tRNA synthetases; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). | 0.443 |
gltX | ftsY | LI0462 | LI0323 | Glutamyl-and glutaminyl-tRNA synthetases; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Signal renition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.491 |
gltX | hemA | LI0462 | LI0322 | Glutamyl-and glutaminyl-tRNA synthetases; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.934 |