node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LI0453 | kdsA | LI0453 | LI0452 | Low specificity phosphatase (HAD superfamily). | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 0.998 |
LI0453 | kdsB | LI0453 | LI0989 | Low specificity phosphatase (HAD superfamily). | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. Belongs to the KdsB family. | 0.996 |
LI0453 | kpsF | LI0453 | LI0083 | Low specificity phosphatase (HAD superfamily). | FOG: CBS domain; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.975 |
carA | kdsB | LI0990 | LI0989 | Carbamoyl-phosphate synthase small chain (Carbamoyl-phosphate synthetase glutamine chain); Belongs to the CarA family. | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. Belongs to the KdsB family. | 0.803 |
kdsA | LI0453 | LI0452 | LI0453 | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | Low specificity phosphatase (HAD superfamily). | 0.998 |
kdsA | kdsB | LI0452 | LI0989 | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. Belongs to the KdsB family. | 0.857 |
kdsA | kdtA | LI0452 | LI0681 | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.744 |
kdsA | kpsF | LI0452 | LI0083 | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | FOG: CBS domain; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.988 |
kdsA | lpxA | LI0452 | LI1019 | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.448 |
kdsA | lpxB | LI0452 | LI1055 | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | Lipid A disaccharide synthetase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.526 |
kdsA | lpxC | LI0452 | LI0627 | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.533 |
kdsA | lpxD | LI0452 | LI1021 | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.451 |
kdsA | lpxK | LI0452 | LI0595 | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | Tetraacyldisaccharide-1-P 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.634 |
kdsB | LI0453 | LI0989 | LI0453 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. Belongs to the KdsB family. | Low specificity phosphatase (HAD superfamily). | 0.996 |
kdsB | carA | LI0989 | LI0990 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. Belongs to the KdsB family. | Carbamoyl-phosphate synthase small chain (Carbamoyl-phosphate synthetase glutamine chain); Belongs to the CarA family. | 0.803 |
kdsB | kdsA | LI0989 | LI0452 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. Belongs to the KdsB family. | 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family. | 0.857 |
kdsB | kdtA | LI0989 | LI0681 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. Belongs to the KdsB family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.982 |
kdsB | kpsF | LI0989 | LI0083 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. Belongs to the KdsB family. | FOG: CBS domain; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.893 |
kdsB | lpxA | LI0989 | LI1019 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. Belongs to the KdsB family. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.599 |
kdsB | lpxB | LI0989 | LI1055 | CMP-2-keto-3-deoxyoctulosonic acid synthetase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. Belongs to the KdsB family. | Lipid A disaccharide synthetase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.646 |