node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddlA | ftsI | LI0682 | LI1098 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | Cell division protein FtsI/penicillin-binding protein 2. | 0.645 |
ddlA | ftsQ | LI0682 | LI1107 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | Cell division septal protein; Essential cell division protein. | 0.895 |
ddlA | mraY | LI0682 | LI1101 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.833 |
ddlA | murB | LI0682 | LI1106 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.960 |
ddlA | murC | LI0682 | LI1105 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.994 |
ddlA | murD | LI0682 | LI1102 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.930 |
ddlA | murE | LI0682 | LI1099 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.781 |
ddlA | murF | LI0682 | LI1100 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.996 |
ddlA | murG | LI0682 | LI1104 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.942 |
ddlA | spoVE | LI0682 | LI1103 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | Bacterial cell division membrane protein; Belongs to the SEDS family. | 0.676 |
ftsI | ddlA | LI1098 | LI0682 | Cell division protein FtsI/penicillin-binding protein 2. | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | 0.645 |
ftsI | ftsQ | LI1098 | LI1107 | Cell division protein FtsI/penicillin-binding protein 2. | Cell division septal protein; Essential cell division protein. | 0.963 |
ftsI | mraY | LI1098 | LI1101 | Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.984 |
ftsI | murB | LI1098 | LI1106 | Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.826 |
ftsI | murC | LI1098 | LI1105 | Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.951 |
ftsI | murD | LI1098 | LI1102 | Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.953 |
ftsI | murE | LI1098 | LI1099 | Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.989 |
ftsI | murF | LI1098 | LI1100 | Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.960 |
ftsI | murG | LI1098 | LI1104 | Cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.935 |
ftsI | spoVE | LI1098 | LI1103 | Cell division protein FtsI/penicillin-binding protein 2. | Bacterial cell division membrane protein; Belongs to the SEDS family. | 0.993 |