node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LI0168 | LI0585 | LI0168 | LI0585 | Superfamily II DNA/RNA helicases, SNF2 family. | DNA repair exonuclease. | 0.646 |
LI0168 | LI0706 | LI0168 | LI0706 | Superfamily II DNA/RNA helicases, SNF2 family. | Uncharacterized conserved protein. | 0.539 |
LI0168 | dnaN | LI0168 | LI0786 | Superfamily II DNA/RNA helicases, SNF2 family. | DNA polymerase sliding clamp subunit (PCNA homolog). | 0.908 |
LI0168 | pcrA | LI0168 | LI0672 | Superfamily II DNA/RNA helicases, SNF2 family. | Superfamily I DNA and RNA helicases. | 0.513 |
LI0168 | polB-2 | LI0168 | LI0102 | Superfamily II DNA/RNA helicases, SNF2 family. | DNA polymerase I-3'-5' exonuclease and polymerase domains. | 0.994 |
LI0168 | recA | LI0168 | LI1182 | Superfamily II DNA/RNA helicases, SNF2 family. | RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.861 |
LI0168 | topA | LI0168 | LI0654 | Superfamily II DNA/RNA helicases, SNF2 family. | Zn-finger domain associated with topoisomerase type I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbro [...] | 0.745 |
LI0585 | LI0168 | LI0585 | LI0168 | DNA repair exonuclease. | Superfamily II DNA/RNA helicases, SNF2 family. | 0.646 |
LI0585 | LI0706 | LI0585 | LI0706 | DNA repair exonuclease. | Uncharacterized conserved protein. | 0.487 |
LI0585 | pcrA | LI0585 | LI0672 | DNA repair exonuclease. | Superfamily I DNA and RNA helicases. | 0.477 |
LI0585 | polB-2 | LI0585 | LI0102 | DNA repair exonuclease. | DNA polymerase I-3'-5' exonuclease and polymerase domains. | 0.999 |
LI0585 | recA | LI0585 | LI1182 | DNA repair exonuclease. | RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.812 |
LI0585 | topA | LI0585 | LI0654 | DNA repair exonuclease. | Zn-finger domain associated with topoisomerase type I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbro [...] | 0.725 |
LI0706 | LI0168 | LI0706 | LI0168 | Uncharacterized conserved protein. | Superfamily II DNA/RNA helicases, SNF2 family. | 0.539 |
LI0706 | LI0585 | LI0706 | LI0585 | Uncharacterized conserved protein. | DNA repair exonuclease. | 0.487 |
LI0706 | dnaN | LI0706 | LI0786 | Uncharacterized conserved protein. | DNA polymerase sliding clamp subunit (PCNA homolog). | 0.884 |
LI0706 | polB-2 | LI0706 | LI0102 | Uncharacterized conserved protein. | DNA polymerase I-3'-5' exonuclease and polymerase domains. | 0.759 |
LI0706 | radA | LI0706 | LI0616 | Uncharacterized conserved protein. | Predicted ATP-dependent serine protease; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.575 |
LI0706 | recA | LI0706 | LI1182 | Uncharacterized conserved protein. | RecA protein (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.862 |
LI0706 | topA | LI0706 | LI0654 | Uncharacterized conserved protein. | Zn-finger domain associated with topoisomerase type I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbro [...] | 0.743 |