node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pnap_0280 | Pnap_0816 | Pnap_0280 | Pnap_0816 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.554 |
Pnap_0280 | miaB | Pnap_0280 | Pnap_3373 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.500 |
Pnap_0280 | rlmN | Pnap_0280 | Pnap_1869 | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.627 |
Pnap_0816 | Pnap_0280 | Pnap_0816 | Pnap_0280 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.554 |
Pnap_0816 | miaB | Pnap_0816 | Pnap_3373 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.590 |
Pnap_0816 | rlmN | Pnap_0816 | Pnap_1869 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.746 |
Pnap_1867 | Pnap_1870 | Pnap_1867 | Pnap_1870 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pol:Bpro_2613 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | 0.487 |
Pnap_1867 | Pnap_1871 | Pnap_1867 | Pnap_1871 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pol:Bpro_2613 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | KEGG: pol:Bpro_2609 hypothetical protein. | 0.423 |
Pnap_1867 | der | Pnap_1867 | Pnap_1876 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pol:Bpro_2613 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.832 |
Pnap_1867 | ispG | Pnap_1867 | Pnap_1872 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pol:Bpro_2613 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.429 |
Pnap_1867 | ndk | Pnap_1867 | Pnap_1868 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pol:Bpro_2613 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.646 |
Pnap_1867 | rlmN | Pnap_1867 | Pnap_1869 | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pol:Bpro_2613 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.673 |
Pnap_1870 | Pnap_1867 | Pnap_1870 | Pnap_1867 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pol:Bpro_2613 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | 0.487 |
Pnap_1870 | Pnap_1871 | Pnap_1870 | Pnap_1871 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | KEGG: pol:Bpro_2609 hypothetical protein. | 0.842 |
Pnap_1870 | der | Pnap_1870 | Pnap_1876 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.550 |
Pnap_1870 | hisS | Pnap_1870 | Pnap_1873 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | KEGG: pol:Bpro_2607 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein. | 0.786 |
Pnap_1870 | ispG | Pnap_1870 | Pnap_1872 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.785 |
Pnap_1870 | ndk | Pnap_1870 | Pnap_1868 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.640 |
Pnap_1870 | rlmN | Pnap_1870 | Pnap_1869 | KEGG: pol:Bpro_2610 tetratricopeptide TPR_2; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.854 |
Pnap_1871 | Pnap_1867 | Pnap_1871 | Pnap_1867 | KEGG: pol:Bpro_2609 hypothetical protein. | PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pol:Bpro_2613 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family. | 0.423 |