STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (115 aa)    
Predicted Functional Partners:
Pnap_1963
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: rme:Rmet_1285 hydrogenase accessory protein HypB.
 
 
 0.977
Pnap_1960
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: rme:Rmet_1282 hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.966
Pnap_1959
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: rme:Rmet_1281 hydrogenase expression/formation protein HypE.
 
  
 0.963
Pnap_1961
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: rme:Rmet_1283 hydrogenase assembly chaperone HypC/HupF.
 
  
 0.963
Pnap_1954
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: rfr:Rfer_4121 hydrogen:quinone oxidoreductase.
 
 
 0.961
Pnap_1962
KEGG: rme:Rmet_1284 hydrogenase maturation protein HypF.
 
   
 0.961
Pnap_1971
Hydrogenase 1 maturation peptidase HyaD, Aspartic peptidase, MEROPS family A31; TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; hydrogenase maturation peptidase superfamily; PFAM: peptidase M52, hydrogen uptake protein; KEGG: rme:Rmet_1293 hydrogenase expression/formation protein.
 
  
 0.929
Pnap_1955
PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: rfr:Rfer_4120 uptake hydrogenase accessory protein HupU.
 
  
 0.926
Pnap_1968
PFAM: HupH hydrogenase expression protein; KEGG: rme:Rmet_1290 HupH hydrogenase expression protein.
 
  
 0.924
Pnap_1965
KEGG: rme:Rmet_1287 hypothetical protein.
 
 
 0.919
Your Current Organism:
Polaromonas naphthalenivorans
NCBI taxonomy Id: 365044
Other names: P. naphthalenivorans CJ2, Polaromonas naphthalenivorans CJ2, Polaromonas naphthalenivorans str. CJ2, Polaromonas naphthalenivorans strain CJ2
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