STRINGSTRING
XP_008439059.1 protein (Cucumis melo) - STRING interaction network
"XP_008439059.1" - DNA topoisomerase in Cucumis melo
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
XP_008439059.1DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (869 aa)    
Predicted Functional Partners:
XP_008463347.1
Tudor domain-containing protein 3 isoform X1 (482 aa)
     
 
  0.952
XP_008446914.1
Crossover junction endonuclease MUS81 isoform X1 (649 aa)
   
 
  0.884
XP_008443143.1
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (938 aa)
     
 
0.836
XP_008449103.1
DNA topoisomerase 1-like; Derived by automated computational analysis using gene prediction method- Gnomon. Supporting evidence includes similarity to- 1 mRNA, 2 ESTs, 7 Proteins, and 100% coverage of the annotated genomic feature by RNAseq alignments, including 18 samples with support for all annotated introns (889 aa)
       
 
  0.808
XP_008446612.1
Uncharacterized protein LOC103489295 (310 aa)
           
  0.790
XP_008445636.1
Uncharacterized protein LOC103488593 (279 aa)
           
  0.790
XP_008460959.1
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (528 aa)
   
   
  0.734
XP_008442370.1
Protein BREAST CANCER SUSCEPTIBILITY 2 homolog B isoform X1; Uncharacterized protein LOC103486259 isoform X1 (1108 aa)
     
 
  0.715
XP_008465894.1
LOW QUALITY PROTEIN- DNA repair endonuclease UVH1; The sequence of the model RefSeq protein was modified relative to its source genomic sequence to represent the inferred CDS- inserted 1 base in 1 codon (1020 aa)
   
 
  0.706
XP_008461811.1
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks (1490 aa)
     
 
  0.652
Your Current Organism:
Cucumis melo
NCBI taxonomy Id: 3656
Other names: C. melo, Cucumis melo, Cucumis melo L., Oriental melon, muskmelon
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