STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcl2Dicer-like protein 2; Dicer-like endonuclease involved in cleaving double- stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons (By similarity) (1388 aa)    
Predicted Functional Partners:
CADNFIAP00005608
RNA-directed RNA polymerase (Sad-1), putative
   
 
 0.833
CADNFIAP00007449
RNA-directed RNA polymerase, putative
   
 
 0.833
CADNFIAP00008705
RNA interference and gene silencing protein (Qde2), putative; Belongs to the argonaute family
   
 
 0.726
CADNFIAP00007132
Arsenite resistance protein Ars2, putative
   
 
 0.720
CADNFIAP00001282
5'->3' exoribonculease Dhp1
   
 
 0.707
CADNFIAP00003745
RNase3 domain protein
   
  
 0.661
CADNFIAP00001748
Histone-lysine n-methyltransferase, suv9
   
 
 0.648
mph1
ATP-dependent DNA helicase mph1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork; Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily
   
 
0.605
CADNFIAP00002182
PAZ domain protein
   
 
 0.587
CADNFIAP00002200
Uncharacterized protein
   
 
 0.587
Your Current Organism:
Neosartorya fischeri
NCBI taxonomy Id: 36630
Other names: Aspergillus fischeri, Aspergillus fischerianus, N. fischeri, Neosartorya fischeri
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