STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dcl1Dicer-like protein 1; Dicer-like endonuclease involved in cleaving double- stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons (By similarity) (1538 aa)    
Predicted Functional Partners:
CADNFIAP00001748
Histone-lysine n-methyltransferase, suv9
   
 
 0.859
CADNFIAP00003745
RNase3 domain protein
   
  
 0.849
CADNFIAP00005599
Uncharacterized protein
   
 
 0.837
CADNFIAP00002182
PAZ domain protein
   
 
 0.826
CADNFIAP00002200
Uncharacterized protein
   
 
 0.826
CADNFIAP00005847
Eukaryotic translation initiation factor 2c; Belongs to the argonaute family
   
 
 0.826
CADNFIAP00005608
RNA-directed RNA polymerase (Sad-1), putative
   
 
 0.807
CADNFIAP00004673
Beta-1,4-mannosyltransferase (Alg1), putative
    
 
 0.779
CADNFIAP00010041
Chromatin regulatory protein sir2
    
 
 0.777
CADNFIAP00007132
Arsenite resistance protein Ars2, putative
   
 
 0.757
Your Current Organism:
Neosartorya fischeri
NCBI taxonomy Id: 36630
Other names: Aspergillus fischeri, Aspergillus fischerianus, N. fischeri, Neosartorya fischeri
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