node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Smed_0165 | Smed_0197 | Smed_0165 | Smed_0197 | Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc02249 putative sensory transduction histidine kinase transmembrane protein. | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | 0.624 |
Smed_0165 | Smed_2490 | Smed_0165 | Smed_2490 | Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc02249 putative sensory transduction histidine kinase transmembrane protein. | KEGG: rso:RS05859 probable peptide synthetase protein. | 0.773 |
Smed_0165 | Smed_2711 | Smed_0165 | Smed_2711 | Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc02249 putative sensory transduction histidine kinase transmembrane protein. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: sme:SMc04028 probable glutamate synthase NADPH large chain protein. | 0.582 |
Smed_0165 | betB | Smed_0165 | Smed_0563 | Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc02249 putative sensory transduction histidine kinase transmembrane protein. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.544 |
Smed_0197 | Smed_0165 | Smed_0197 | Smed_0165 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sme:SMc02249 putative sensory transduction histidine kinase transmembrane protein. | 0.624 |
Smed_0197 | Smed_0371 | Smed_0197 | Smed_0371 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: rle:pRL120289 putative choline dehydrogenase. | 0.445 |
Smed_0197 | Smed_0564 | Smed_0197 | Smed_0564 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | PFAM: sulfatase; KEGG: sme:SMc00127 choline sulfatase protein. | 0.571 |
Smed_0197 | Smed_2490 | Smed_0197 | Smed_2490 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | KEGG: rso:RS05859 probable peptide synthetase protein. | 0.999 |
Smed_0197 | Smed_2711 | Smed_0197 | Smed_2711 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: sme:SMc04028 probable glutamate synthase NADPH large chain protein. | 0.463 |
Smed_0197 | betA | Smed_0197 | Smed_0562 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.445 |
Smed_0197 | betB | Smed_0197 | Smed_0563 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.583 |
Smed_0197 | betI | Smed_0197 | Smed_0565 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | Transcriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes. | 0.419 |
Smed_0197 | fmt | Smed_0197 | Smed_0055 | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.587 |
Smed_0371 | Smed_0197 | Smed_0371 | Smed_0197 | PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: rle:pRL120289 putative choline dehydrogenase. | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | 0.445 |
Smed_0371 | betA | Smed_0371 | Smed_0562 | PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: rle:pRL120289 putative choline dehydrogenase. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.919 |
Smed_0371 | betB | Smed_0371 | Smed_0563 | PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: rle:pRL120289 putative choline dehydrogenase. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.908 |
Smed_0564 | Smed_0197 | Smed_0564 | Smed_0197 | PFAM: sulfatase; KEGG: sme:SMc00127 choline sulfatase protein. | Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: sme:SMc02273 fatty acid synthase transmembrane protein. | 0.571 |
Smed_0564 | betA | Smed_0564 | Smed_0562 | PFAM: sulfatase; KEGG: sme:SMc00127 choline sulfatase protein. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.484 |
Smed_0564 | betB | Smed_0564 | Smed_0563 | PFAM: sulfatase; KEGG: sme:SMc00127 choline sulfatase protein. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.799 |
Smed_0564 | betI | Smed_0564 | Smed_0565 | PFAM: sulfatase; KEGG: sme:SMc00127 choline sulfatase protein. | Transcriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes. | 0.668 |