node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Smed_2526 | argS | Smed_2526 | Smed_1158 | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sme:SMc00735 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | 0.851 |
Smed_2526 | guaA | Smed_2526 | Smed_3517 | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sme:SMc00735 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.762 |
Smed_2526 | ileS | Smed_2526 | Smed_0412 | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sme:SMc00735 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | 0.896 |
Smed_2526 | leuS | Smed_2526 | Smed_3198 | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sme:SMc00735 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | TIGRFAM: leucyl-tRNA synthetase; KEGG: sme:SMc02804 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.880 |
Smed_2526 | lysS | Smed_2526 | Smed_2800 | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sme:SMc00735 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: sme:SMc03173 lysyl-tRNA synthetase protein; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.861 |
Smed_2526 | metG | Smed_2526 | Smed_1290 | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sme:SMc00735 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.886 |
Smed_2526 | pheT | Smed_2526 | Smed_3487 | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sme:SMc00735 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: sme:SMc00366 probable phenylalanyl-tRNA synthetase beta chain protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.825 |
Smed_2526 | proS | Smed_2526 | Smed_0918 | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sme:SMc00735 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.877 |
Smed_2526 | pyrG | Smed_2526 | Smed_1069 | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sme:SMc00735 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.639 |
argS | Smed_2526 | Smed_1158 | Smed_2526 | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sme:SMc00735 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.851 |
argS | gltX | Smed_1158 | Smed_2799 | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.888 |
argS | guaA | Smed_1158 | Smed_3517 | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.979 |
argS | ileS | Smed_1158 | Smed_0412 | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | 0.954 |
argS | leuS | Smed_1158 | Smed_3198 | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | TIGRFAM: leucyl-tRNA synthetase; KEGG: sme:SMc02804 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.880 |
argS | lysS | Smed_1158 | Smed_2800 | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: sme:SMc03173 lysyl-tRNA synthetase protein; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.890 |
argS | metG | Smed_1158 | Smed_1290 | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.918 |
argS | pheT | Smed_1158 | Smed_3487 | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: sme:SMc00366 probable phenylalanyl-tRNA synthetase beta chain protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.863 |
argS | proS | Smed_1158 | Smed_0918 | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. | 0.940 |
argS | pyrG | Smed_1158 | Smed_1069 | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.823 |
gltX | argS | Smed_2799 | Smed_1158 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | TIGRFAM: arginyl-tRNA synthetase; KEGG: sme:SMc02073 probable arginyl-tRNA synthetase (arginine--tRNA ligase) protein. | 0.888 |