node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MurQ | Smed_1160 | Smed_3406 | Smed_1160 | PFAM: sugar isomerase (SIS); KEGG: sme:SMc02874 hypothetical protein. | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase family 3 domain protein; KEGG: sme:SMc02071 putative hydrolase glycosidase protein. | 0.587 |
MurQ | anmK | Smed_3406 | Smed_1472 | PFAM: sugar isomerase (SIS); KEGG: sme:SMc02874 hypothetical protein. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.955 |
Smed_0818 | anmK | Smed_0818 | Smed_1472 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.536 |
Smed_1160 | MurQ | Smed_1160 | Smed_3406 | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase family 3 domain protein; KEGG: sme:SMc02071 putative hydrolase glycosidase protein. | PFAM: sugar isomerase (SIS); KEGG: sme:SMc02874 hypothetical protein. | 0.587 |
Smed_1160 | Smed_2104 | Smed_1160 | Smed_2104 | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase family 3 domain protein; KEGG: sme:SMc02071 putative hydrolase glycosidase protein. | PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sme:SMc01854 N-acetylmuramoyl-L-alanine amidase. | 0.811 |
Smed_1160 | anmK | Smed_1160 | Smed_1472 | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase family 3 domain protein; KEGG: sme:SMc02071 putative hydrolase glycosidase protein. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.840 |
Smed_1471 | anmK | Smed_1471 | Smed_1472 | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sme:SMb20523 hypothetical protein transmembrane. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.544 |
Smed_2104 | Smed_1160 | Smed_2104 | Smed_1160 | PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sme:SMc01854 N-acetylmuramoyl-L-alanine amidase. | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase family 3 domain protein; KEGG: sme:SMc02071 putative hydrolase glycosidase protein. | 0.811 |
Smed_2104 | anmK | Smed_2104 | Smed_1472 | PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sme:SMc01854 N-acetylmuramoyl-L-alanine amidase. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.546 |
anmK | MurQ | Smed_1472 | Smed_3406 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | PFAM: sugar isomerase (SIS); KEGG: sme:SMc02874 hypothetical protein. | 0.955 |
anmK | Smed_0818 | Smed_1472 | Smed_0818 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.536 |
anmK | Smed_1160 | Smed_1472 | Smed_1160 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase family 3 domain protein; KEGG: sme:SMc02071 putative hydrolase glycosidase protein. | 0.840 |
anmK | Smed_1471 | Smed_1472 | Smed_1471 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sme:SMb20523 hypothetical protein transmembrane. | 0.544 |
anmK | Smed_2104 | Smed_1472 | Smed_2104 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: sme:SMc01854 N-acetylmuramoyl-L-alanine amidase. | 0.546 |
anmK | gcvP | Smed_1472 | Smed_1182 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.444 |
anmK | tyrS | Smed_1472 | Smed_1473 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.573 |
gcvP | anmK | Smed_1182 | Smed_1472 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.444 |
tyrS | anmK | Smed_1473 | Smed_1472 | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.573 |