STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (291 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.999
Smed_2317
PFAM: aminotransferase class-III; KEGG: sme:SMc01534 beta alanine-pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.915
Smed_3162
PFAM: aminotransferase class-III; KEGG: sme:SMc04388 putative omega-amino acid--pyruvate aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.915
coaA
TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: sme:SMc02567 probable pantothenate kinase protein.
     
 0.910
Smed_3566
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.910
cmk
TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: sme:SMc00334 putative cytidylate kinase (CMP kinase) protein.
      0.906
Smed_2414
PFAM: aldehyde dehydrogenase; KEGG: sme:SMc01971 putative aldehyde dehydrogenase protein; Belongs to the aldehyde dehydrogenase family.
     
 0.900
Smed_3159
PFAM: aldehyde dehydrogenase; KEGG: sme:SMc04385 putative aldehyde dehydrogenase transmembrane protein; Belongs to the aldehyde dehydrogenase family.
     
 0.900
Smed_0818
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
   
 0.618
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
 
   
 0.589
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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