STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsdATIGRFAM: D-serine ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ajs:Ajs_2250 D-serine ammonia-lyase; Belongs to the serine/threonine dehydratase family. DsdA subfamily. (442 aa)    
Predicted Functional Partners:
Smed_1037
TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: sme:SMc01256 probable L-serine dehydratase protein; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.915
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
 0.910
Smed_3362
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sme:SMc02828 putative hydroxyacid dehydrogenase protein.
  
  
  0.823
Smed_1450
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sme:SMc00290 probable lactoylglutathione lyase methylglyoxalase protein.
     
  0.800
Smed_2446
PFAM: aldehyde dehydrogenase; KEGG: mpt:Mpe_A0361 lactaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
  0.800
dadA
D-amino-acid dehydrogenase; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family.
 
     0.663
folD2
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
     
 0.507
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
       0.488
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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