STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (427 aa)    
Predicted Functional Partners:
Caul_3653
KEGG: ccr:CC_2533 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
 0.996
Caul_0412
Fumarylacetoacetase; KEGG: swi:Swit_3863 fumarylacetoacetase; TIGRFAM: fumarylacetoacetase; PFAM: fumarylacetoacetate (FAA) hydrolase; Domain of unknown function DUF1969.
 
  
 0.969
Caul_0071
TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain; KEGG: ccr:CC_3568 glutathione S-transferase family protein.
 
 
 0.960
Caul_3651
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: ccr:CC_2531 fumarylacetoacetate hydrolase family protein.
 
  
 0.911
Caul_2208
TIGRFAM: phenylalanine-4-hydroxylase; PFAM: aromatic amino acid hydroxylase; KEGG: ccr:CC_1612 phenylalanine-4-hydroxylase.
 
  
 0.885
Caul_4648
PFAM: transcriptional coactivator/pterin dehydratase; KEGG: ccr:CC_0245 pterin-4-alpha-carbinolamine dehydratase.
 
  
 0.755
Caul_3650
PFAM: Rieske [2Fe-2S] domain protein; KEGG: mxa:MXAN_2788 Rieske 2Fe-2S domain protein.
 
     0.728
Caul_0072
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: ccr:CC_3567 fumarylacetoacetate hydrolase family protein.
  
  
 0.716
Caul_0486
KEGG: pla:Plav_0538 hypothetical protein.
  
 
 0.676
Caul_0487
KEGG: hne:HNE_1472 hypothetical protein.
  
 
 0.676
Your Current Organism:
Caulobacter sp. K31
NCBI taxonomy Id: 366602
Other names: C. sp. K31
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