STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)    
Predicted Functional Partners:
Caul_0483
TIGRFAM: DNA binding domain protein, excisionase family; PFAM: regulatory protein MerR; Citrate synthase; KEGG: bxe:Bxe_A1721 excisionase/Xis, DNA-binding.
  
 0.973
Caul_2787
KEGG: ccr:CC_1906 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.
  
 0.973
Caul_4948
PFAM: Citrate synthase; KEGG: ccr:CC_3642 citrate synthase; Belongs to the citrate synthase family.
  
 0.973
Caul_4949
PFAM: Citrate synthase; KEGG: ccr:CC_3643 citrate synthase.
  
 0.973
Caul_3722
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: ccr:CC_2622 NADP-dependent malic enzyme.
  
 0.972
Caul_4968
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: ccr:CC_3549 NADP-dependent malic enzyme.
  
 0.972
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.970
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.946
Caul_3527
KEGG: ccr:CC_2522 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 
 0.939
Caul_1479
PFAM: aminotransferase class I and II; KEGG: ccr:CC_1534 aspartate aminotransferase.
  
 0.923
Your Current Organism:
Caulobacter sp. K31
NCBI taxonomy Id: 366602
Other names: C. sp. K31
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