STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
luxSAutoinducer-2 production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (171 aa)    
Predicted Functional Partners:
pfs
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
 
 
 0.981
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.950
metC1
Cystathionine gamma-synthase; Pfam match to PF01053 Cys_Met_Meta_PP, score 370.5, E-value 2.4E-108.
 
 
 0.940
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
    
 0.933
metC2
Cystathionine gamma-synthase; Pfam match to PF01053 Cys_Met_Meta_PP, score -144.4, E-value 4.7E-011.
  
 
 0.927
metY
O-acetylhomoserine sulfhydrylase; Pfam match to PF01053 Cys_Met_Meta_PP, score 560.2, E-value 2E-165.
     
 0.904
Abu_0316
aminotransferase/L-cysteine desulfhydrase; Pfam match to PF00155 Aminotran_1_2, score 101.4, E-value 3.3E-028.
     
  0.900
cysK1
Cysteine synthase; Pfam match to PF00291 PALP, score 420.1, E-value 2.8E-123; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.854
hom
Pfam matches to PF00742 Homoserine_dh, score 279.2, E-value 7.3E-081, and to PF03447 NAD_binding_3, score 62.7, E-value 6.8E-017, and to PF01842 ACT, score 43.8, E-value 1.5E-011.
     
 0.813
ilvA
Threonine deaminase; Pfam match to PF00291 PALP, score 266.2, E-value 6.1E-077.
     
 0.804
Your Current Organism:
Arcobacter butzleri
NCBI taxonomy Id: 367737
Other names: A. butzleri RM4018, Arcobacter butzleri RM4018, Arcobacter butzleri str. RM4018, Arcobacter butzleri strain RM4018
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