STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase; Pfam match to PF00202 Aminotran_3, score 304.1, E-value 2.4E-088. (426 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase; Pfam match to PF00490 ALAD, score 616.6, E-value 2E-182; Belongs to the ALAD family.
 
 
 0.991
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.988
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.919
dltA
D-alanine activating enzyme; Pfam match to PF00501 AMP-binding, score 298.6, E-value 1.1E-086.
 
  
 0.876
Abu_1008
Conserved hypothetical protein.
  
    0.764
Abu_1009
Conserved hypothetical protein.
       0.760
ppnP-2
Conserved hypothetical protein (DUF1255 domain protein); Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
       0.748
nrfI
Cytochrome c biogenesis protein; Pfam match to PF01578 Cytochrom_C_asm, score 146.5, E-value 6.5E-041.
  
  
 0.659
Abu_1304
Cytochrome c biogenesis protein; Pfam match to PF01578 Cytochrom_C_asm, score 147, E-value 4.6E-041.
  
  
 0.659
cysG
Uroporphyrin III C-methyltransferase; Pfam match to PF00590 TP_methylase, score 265.7, E-value 8.7E-077; non-fusion protein; does not contain precorrin-2 dehydrogenase or sirohydrochlorin ferrochelatase activity; Belongs to the precorrin methyltransferase family.
 
   
 0.619
Your Current Organism:
Arcobacter butzleri
NCBI taxonomy Id: 367737
Other names: A. butzleri RM4018, Arcobacter butzleri RM4018, Arcobacter butzleri str. RM4018, Arcobacter butzleri strain RM4018
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.