STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hisCHistidinol-phosphate aminotransferase; Pfam match to PF00155 Aminotran_1_2, score 176.4, E-value 6.6E-050; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (367 aa)    
Predicted Functional Partners:
hisI
Bifunctional phosphoribosyl-AMP cyclohydrolase/ phosphoribosyl-ATP pyrophosphohydrolase; Pfam matches to PF01502 PRA-CH, score 173.5, E-value 4.8E-049, and to PF01503 PRA-PH, score 98.2, E-value 2.2E-026; In the N-terminal section; belongs to the PRA-CH family.
 
  
 0.999
hisB
Imidazoleglycerol-phosphate dehydratase; Pfam match to PF00475 IGPD, score 259.8, E-value 5.1E-075.
 
 0.999
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 0.994
pheA
Bifunctional chorismate mutase/prephenate dehydratase; Pfam matches to PF00800 PDT, score 149.3, E-value 9.1E-042, and to PF01817 CM_2, score 87.3, E-value 4.2E-023, and to PF01842 ACT, score 27.3, E-value 6.3E-007.
  
 
 0.988
tyrA
Prephenate dehydrogenase; Pfam match to PF02153 PDH, score 323.9, E-value 2.5E-094.
  
 
 0.985
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
 
  
 0.934
aspB3
Aspartate aminotransferase, aminotransferase, classes I and II; Pfam match to PF00155 Aminotran_1_2, score 287.2, E-value 2.8E-083.
 
 
 0.934
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Pfam match to PF00977 His_biosynth, score 351.6, E-value 1.2E-102.
  
  
 0.925
hisJ
Histidinol-phosphate phosphatase; Pfam match to PF02811 PHP, score 66.9, E-value 2.2E-019; Belongs to the PHP hydrolase family. HisK subfamily.
  
 
 0.925
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
 0.904
Your Current Organism:
Arcobacter butzleri
NCBI taxonomy Id: 367737
Other names: A. butzleri RM4018, Arcobacter butzleri RM4018, Arcobacter butzleri str. RM4018, Arcobacter butzleri strain RM4018
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.