STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (249 aa)    
Predicted Functional Partners:
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.987
tsf
Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
 
  
 0.979
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.975
BAD_0537
COG family:orotidine-5'-phosphate decarboxylase; Omp decarboxylase; Ompdcase; Orthologue of BL0069.
   
 
 0.959
pyrF
COG family:orotidine-5'-phosphate decarboxylase; OMP decarboxylase; Orthologue of BL0791; Belongs to the OMP decarboxylase family. Type 2 subfamily.
   
 
 0.959
rpsB
30S ribosomal protein S2; Essential for binding of S1 to the small ribosomalsubunit; Orthologue of BL1503; Belongs to the universal ribosomal protein uS2 family.
 
  
 0.896
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
  
 0.822
cdsA
Probable phosphatidate cytidylyltransferase; CDP-diglyceride synthetase; COGfamily: CDP-diglyceride synthetase; Orthologue of BL1507; PFAM_ID:Cytidylyltrans.
 
  
 0.760
pheT
phenylalanyl-tRNA synthetase beta chain; Catalyzes a two-step reaction_ first charging aphenylalanine molecule by linking its carboxyl group tothe alpha-phosphate of ATP_ followed by transfer of theaminoacyl-adenylate to its tRNA; Orthologue of Tfu_2060_BL1066; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.754
rplS
Putative 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
  
 0.721
Your Current Organism:
Bifidobacterium adolescentis
NCBI taxonomy Id: 367928
Other names: B. adolescentis ATCC 15703, Bifidobacterium adolescentis ATCC 15703, Bifidobacterium adolescentis str. ATCC 15703, Bifidobacterium adolescentis strain ATCC 15703
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